INT327021

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Context Info
Confidence 0.33
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.26
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Myog) nucleus (Myog) DNA binding (Myog)
Anatomy Link Frequency
muscle 3
Myog (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 18 46.48 Quite Low
fibrosis 5 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Appetite Loss 42 99.28 Very High Very High Very High
Cancer 86 98.92 Very High Very High Very High
Injury 14 95.72 Very High Very High Very High
Muscle Disease 4 74.72 Quite High
Frailty 40 65.04 Quite High
Muscular Atrophy 28 57.56 Quite High
Aging 8 55.72 Quite High
Birth Weight 9 50.96 Quite High
Body Weight 14 5.00 Very Low Very Low Very Low
Carcinoma 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Regeneration of glycerol-injured soleus muscles, myogenin expression, and Akt phosphorylation were suppressed in muscles isolated from As2O3-treated mice compared with untreated mice.


Phosphorylation (phosphorylation) of myogenin in muscles
1) Confidence 0.33 Published 2010 Journal Environ Health Perspect Section Abstract Doc Link PMC2920914 Disease Relevance 0.22 Pain Relevance 0
These observations point to myogenin phosphorylation as a putative mechanism for impaired muscle regenerative response in cancer cachexia.
Phosphorylation (phosphorylation) of myogenin in muscle associated with appetite loss and cancer
2) Confidence 0.26 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2965098 Disease Relevance 0.56 Pain Relevance 0
In this regard, phosphorylation in the myogenin transcriptional domain was shown to inhibit the induction of muscle specific genes [21].


Phosphorylation (phosphorylation) of myogenin in muscle
3) Confidence 0.26 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2965098 Disease Relevance 0.48 Pain Relevance 0

General Comments

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