INT327027

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Context Info
Confidence 0.24
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.86
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Myog) nucleus (Myog) DNA binding (Myog)
Anatomy Link Frequency
muscles 2
Myog (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 10 32.92 Quite Low
cytokine 9 9.32 Low Low
Inflammation 5 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
dexamethasone 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 22 98.76 Very High Very High Very High
Muscular Dystrophy 2 95.24 Very High Very High Very High
Chronic Renal Failure 1 89.84 High High
Muscle Disease 8 89.56 High High
Cancer 43 87.04 High High
Hepatocellular Cancer 3 85.88 High High
Apoptosis 7 65.76 Quite High
Acute Promyelocytic Leukemia 2 54.48 Quite High
Frailty 20 50.00 Quite Low
Appetite Loss 21 48.84 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study, using morphologic examination, we also found that As2O3 (0.5 and 5 ppm) effectively suppressed myogenin expression and retarded muscle regeneration in mouse soleus muscles after injury by glycerol.
Regulation (regeneration) of Gene_expression (expression) of myogenin in muscles associated with injury
1) Confidence 0.24 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2920914 Disease Relevance 0.46 Pain Relevance 0
The present study suggests an alternative mechanism based on ERK activation: when the C26 hosts are treated with PD, and ERK is thus inhibited, Pax7 and myogenin expression is restored to control values.
Regulation (control) of Gene_expression (expression) of myogenin
2) Confidence 0.19 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2965098 Disease Relevance 0.40 Pain Relevance 0
We next investigated the effect of As2O3 on myogenin expression during myogenic differentiation using immunocytochemistry (Figure 4) and Western blotting (Figure 5A).
Spec (investigated) Regulation (effect) of Gene_expression (expression) of myogenin
3) Confidence 0.14 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2920914 Disease Relevance 0 Pain Relevance 0

General Comments

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