INT32711

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Context Info
Confidence 0.54
First Reported 1988
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.92
Pain Relevance 1.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CALCB) extracellular region (CALCB)
Anatomy Link Frequency
larynx 1
CALCB (Homo sapiens)
Pain Link Frequency Relevance Heat
calcitonin gene related peptide 2 100.00 Very High Very High Very High
substance P 2 100.00 Very High Very High Very High
Glutamate 1 100.00 Very High Very High Very High
Analgesic 1 99.24 Very High Very High Very High
Pain 1 98.72 Very High Very High Very High
qutenza 9 98.42 Very High Very High Very High
Nicotine 3 92.60 High High
Central nervous system 2 90.56 High High
c fibre 1 66.80 Quite High
Disease Link Frequency Relevance Heat
Pain 1 98.72 Very High Very High Very High
Cough 9 93.48 High High
Dyspnea 1 84.04 Quite High
Paresis 1 79.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pretreatment of adult guinea-pigs with capsaicin (50 mg kg-1 s.c.) produced a long-lasting (greater than or equal to 10 weeks) depletion of substance P- and calcitonin gene related peptide-like immunoreactivities in the sensory nerves of the larynx, tracheobronchial tree and lung.
Negative_regulation (depletion) of calcitonin gene in larynx associated with calcitonin gene related peptide, qutenza and substance p
1) Confidence 0.54 Published 1988 Journal Pulm Pharmacol Section Abstract Doc Link 2980286 Disease Relevance 0.74 Pain Relevance 0.95
Reduction of formalin-induced pain suggests direct analgesic BT effects possibly mediated through blockade of substance P, glutamate and calcitonin gene related peptide.
Negative_regulation (blockade) of calcitonin gene associated with calcitonin gene related peptide, pain, glutamate, analgesic and substance p
2) Confidence 0.03 Published 2005 Journal Arq Neuropsiquiatr Section Abstract Doc Link 15830090 Disease Relevance 0.18 Pain Relevance 0.44

General Comments

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