INT32715

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Context Info
Confidence 0.34
First Reported 1985
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.09
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Prl)
Prl (Rattus norvegicus)
LH (Rattus norvegicus)
Pain Link Frequency Relevance Heat
narcan 2 99.18 Very High Very High Very High
Dopamine 13 98.48 Very High Very High Very High
agonist 22 98.12 Very High Very High Very High
opioid receptor 3 97.76 Very High Very High Very High
antagonist 44 97.12 Very High Very High Very High
Opioid 2 84.56 Quite High
Nerve growth factor 28 5.00 Very Low Very Low Very Low
Inflammation 27 5.00 Very Low Very Low Very Low
cytokine 22 5.00 Very Low Very Low Very Low
Calcitonin gene-related peptide 17 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 48 89.48 High High
INFLAMMATION 28 5.00 Very Low Very Low Very Low
Cancer 22 5.00 Very Low Very Low Very Low
Targeted Disruption 22 5.00 Very Low Very Low Very Low
Pituitary Cancer 11 5.00 Very Low Very Low Very Low
Starvation 10 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 8 5.00 Very Low Very Low Very Low
Natriuresis 7 5.00 Very Low Very Low Very Low
Adhesions 6 5.00 Very Low Very Low Very Low
Hyperplasia 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Possible delta receptor mediation of the effect of beta-endorphin on luteinizing hormone (LH) release, but not on prolactin (PRL) release, in the ovariectomized rat.
PRL Regulation (effect) of Localization (release) of LH associated with narcan
1) Confidence 0.34 Published 1985 Journal Endocrinology Section Title Doc Link 2981076 Disease Relevance 0 Pain Relevance 0.49
In sheep, PRL on its own was found to inhibit (305) or not affect (306) GnRH-induced LH release in culture but, in the presence of a dopamine agonist, it completely blocked it, at least when cells are taken in the nonbreeding season (306).
PRL Neg (not) Regulation (affect) of Localization (release) of LH associated with dopamine and agonist
2) Confidence 0.03 Published 2008 Journal Journal of Neuroendocrinology Section Body Doc Link PMC2229370 Disease Relevance 0.09 Pain Relevance 0.19

General Comments

This test has worked.

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