INT32717

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Context Info
Confidence 0.00
First Reported 1984
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.43
Pain Relevance 1.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (ENG) cell motility (ENG) cell adhesion (ENG)
nucleolus (ENG) nucleus (ENG) cytoplasm (ENG)
Anatomy Link Frequency
hypothalamus 2
plasma 2
ENG (Homo sapiens)
Pain Link Frequency Relevance Heat
dexamethasone 4 99.84 Very High Very High Very High
antagonist 6 99.00 Very High Very High Very High
narcan 6 98.54 Very High Very High Very High
Opioid 1 94.72 High High
agonist 3 94.68 High High
opioid receptor 2 84.20 Quite High
opiate 4 77.40 Quite High
fluoxetine 1 68.32 Quite High
Disease Link Frequency Relevance Heat
Stress 9 99.44 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The delta antagonist ICI 154, 129, but not the mu1 or mu antagonists naloxazone or beta-funaltrexamine, respectively, blocked the suppressive effect of beta-END on plasma LH levels and transiently but significantly increased LH levels above preinfusion value.
Negative_regulation (blocked) of Regulation (effect) of beta-END in plasma associated with antagonist
1) Confidence 0.00 Published 1985 Journal Endocrinology Section Abstract Doc Link 2981076 Disease Relevance 0 Pain Relevance 0.41
Bilateral lesion of the posterior hypothalamus inhibited the ACTH, beta-END and PRL responses to restraint stress, ether stress and LPS endotoxin, whereas sham operation had no effect compared to nonoperated control rats.
Negative_regulation (inhibited) of Regulation (responses) of beta-END in hypothalamus associated with stress
2) Confidence 0.00 Published 1999 Journal Neuroendocrinology Section Abstract Doc Link 9892850 Disease Relevance 0.43 Pain Relevance 0.24
NAL blocked the GH rise and depressed TSH levels, but did not significantly inhibit the PRL or beta-END-LI response.
Negative_regulation (inhibit) of Regulation (response) of beta-END associated with narcan
3) Confidence 0.00 Published 1984 Journal Endocrinology Section Abstract Doc Link 6323136 Disease Relevance 0 Pain Relevance 0.60

General Comments

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