INT327200

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Context Info
Confidence 0.23
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 7
Disease Relevance 0.94
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (ESRRA) nucleus (ESRRA) DNA binding (ESRRA)
Anatomy Link Frequency
myoblasts 2
ESRRA (Homo sapiens)
Pain Link Frequency Relevance Heat
transdermal 5 92.64 High High
Somatostatin 7 79.04 Quite High
ischemia 57 74.08 Quite High
addiction 2 47.04 Quite Low
antagonist 20 31.04 Quite Low
depression 5 20.92 Low Low
agonist 23 5.00 Very Low Very Low Very Low
vaginimus 14 5.00 Very Low Very Low Very Low
antidepressant 12 5.00 Very Low Very Low Very Low
Inflammation 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Reprotox - General 1 98 92.64 High High
Cancer 12 87.88 High High
Cytomegalovirus Infection 10 85.76 High High
Diabetes Mellitus 245 81.76 Quite High
Cv Unclassified Under Development 37 74.08 Quite High
Reprotox - General 3 10 67.44 Quite High
Endometriosis (extended) 24 64.72 Quite High
Hypoglycemia 4 57.08 Quite High
Recurrence 8 51.76 Quite High
Appetite Loss 13 50.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
When co-transfected with an ERR?
Positive_regulation (transfected) of Gene_expression (transfected) of ERR
1) Confidence 0.23 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2933242 Disease Relevance 0 Pain Relevance 0
PPARA promoter-reporter constructs were cotransfected with empty expression vector or vector expressing ERR?
Positive_regulation (cotransfected) of Gene_expression (cotransfected) of ERR
2) Confidence 0.23 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2933242 Disease Relevance 0.16 Pain Relevance 0
54,642 A was observed with ERR?
Positive_regulation (observed) of Gene_expression (observed) of ERR
3) Confidence 0.23 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2933242 Disease Relevance 0 Pain Relevance 0
in C2C12 myoblasts was masking PPARA/TK A promoter-reporter activation by transfected ERR?
Positive_regulation (transfected) of Gene_expression (transfected) of ERR in myoblasts
4) Confidence 0.23 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2933242 Disease Relevance 0.05 Pain Relevance 0
Again, the results were similar with co-transfection of ERR?
Positive_regulation (transfection) of Gene_expression (transfection) of ERR
5) Confidence 0.23 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2933242 Disease Relevance 0.16 Pain Relevance 0.04
Compared to E2 administration alone, testosterone reduced E2-induced proliferation by approximately 40% and entirely abolished E2-induced augmentation of estrogen receptor alpha expression [36].
Positive_regulation (augmentation) of Gene_expression (expression) of estrogen receptor alpha
6) Confidence 0.05 Published 2010 Journal J Cancer Surviv Section Body Doc Link PMC2921487 Disease Relevance 0.42 Pain Relevance 0
Gastric ghrelin-secreting cells express estrogen receptor-alpha [103], thus potentially mediating some sex-steroid effects.
Positive_regulation (mediating) of Gene_expression (express) of estrogen receptor-alpha
7) Confidence 0.04 Published 2010 Journal International Journal of Peptides Section Body Doc Link PMC2925380 Disease Relevance 0.16 Pain Relevance 0.12

General Comments

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