INT327234
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
A number of RNA-binding proteins, e.g., HuR and PTB (polypyrimidine tract-binding protein), bind to U-rich/AU-rich region of VEGF and HIF 3? | |||||||||||||||
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These events allow the prevalence of HuR stabilizing action. | |||||||||||||||
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Knockdown of HuR also leads to decreased cellular growth and VEGF expression in colorectal cancer cells [144]. miR-519 represses HuR translation, in turn reducing HuR-regulated gene expression and cell division [145]. | |||||||||||||||
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Knockdown of HuR also leads to decreased cellular growth and VEGF expression in colorectal cancer cells [144]. miR-519 represses HuR translation, in turn reducing HuR-regulated gene expression and cell division [145]. | |||||||||||||||
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General Comments
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