INT327283

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Context Info
Confidence 0.39
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.50
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Zfp36) mRNA binding (Zfp36) nucleus (Zfp36)
DNA binding (Zfp36) response to stress (Zfp36) cytoplasm (Zfp36)
Anatomy Link Frequency
finger 1
Zfp36 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 116 74.12 Quite High
chemokine 10 58.08 Quite High
cytokine 33 57.60 Quite High
Inflammatory response 4 47.60 Quite Low
cINOD 5 5.00 Very Low Very Low Very Low
Arthritis 5 5.00 Very Low Very Low Very Low
Kinase C 4 5.00 Very Low Very Low Very Low
Inflammatory stimuli 3 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperplasia 5 76.48 Quite High
INFLAMMATION 120 74.12 Quite High
Cancer 144 61.92 Quite High
Stress 3 58.88 Quite High
Hypoxia 11 54.60 Quite High
Disease 9 44.16 Quite Low
Metastasis 9 43.00 Quite Low
Apoptosis 4 41.44 Quite Low
Colon Cancer 8 5.00 Very Low Very Low Very Low
Colitis 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These are modulated during cellular stimulation by inactivation of RNA decay-promoting proteins such as zinc-finger protein, tristetraprolin (TTP) [4], K-homology splicing-regulatory protein (KSRP) [5], butyrate response factor 1 and 2 [6], and certain gene products of the AU-rich element (ARE)/poly(U)-binding/degradation factor 1 (AUF1) [7].
Negative_regulation (inactivation) of tristetraprolin in finger
1) Confidence 0.39 Published 2010 Journal Cell Mol Life Sci Section Body Doc Link PMC2921490 Disease Relevance 0.50 Pain Relevance 0.18

General Comments

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