INT327312

Context Info Confidence 0.03 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.45 Pain Relevance 0.19

cytoplasm (Ttpa, Elavl1) cytosol (Ttpa) transport (Ttpa) RNA binding (Elavl1) nucleus (Elavl1) intracellular (Ttpa)

Ttpa (Mus musculus) Elavl1 (Mus musculus)

Pain Link Frequency Relevance Heat Inflammation 116 91.20 cytokine 33 90.16 Inflammatory stimuli 3 83.60 chemokine 10 5.00 cINOD 5 5.00 Arthritis 5 5.00 Inflammatory response 4 5.00 Kinase C 4 5.00 aspirin 1 5.00 Inflammatory mediators 1 5.00

Disease Link Frequency Relevance Heat INFLAMMATION 120 91.20 Cancer 144 80.52 Targeted Disruption 6 30.88 Bacterial Infection 1 27.52 Shock 1 10.56 Hypoxia 11 5.00 Metastasis 9 5.00 Disease 9 5.00 Colon Cancer 8 5.00 Colitis 6 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Ectopic expression of HuR overcomes TTP-mediated destabilization of IL-3 mRNA and HuR mRNA in an ARE-dependent manner [69, 73].

Positive_regulation (overcomes) of TTP Negative_regulation (destabilization) of HuR mRNA

1) Confidence 0.03 Published 2010 Journal Cell Mol Life Sci Section Body Doc Link PMC2921490 Disease Relevance 0.45 Pain Relevance 0.19

General Comments

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