INT327328

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.74
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

RNA binding (Hnrnpd, Elavl1) nucleus (Hnrnpd, Elavl1) cytoplasm (Hnrnpd, Elavl1)
cytosol (Hnrnpd) DNA binding (Hnrnpd)
Hnrnpd (Mus musculus)
Elavl1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory stimuli 6 93.68 High High
Inflammation 232 81.20 Quite High
cytokine 66 80.16 Quite High
chemokine 20 5.00 Very Low Very Low Very Low
cINOD 10 5.00 Very Low Very Low Very Low
Arthritis 10 5.00 Very Low Very Low Very Low
Inflammatory response 8 5.00 Very Low Very Low Very Low
Kinase C 8 5.00 Very Low Very Low Very Low
aspirin 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 240 93.36 High High
Cancer 288 90.60 High High
Targeted Disruption 12 20.88 Low Low
Bacterial Infection 2 17.52 Low Low
Hypoxia 22 5.00 Very Low Very Low Very Low
Metastasis 18 5.00 Very Low Very Low Very Low
Disease 18 5.00 Very Low Very Low Very Low
Colon Cancer 16 5.00 Very Low Very Low Very Low
Colitis 12 5.00 Very Low Very Low Very Low
Hyperplasia 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A specific example is that siRNA-mediated knockdown of HuR led to larger AUF1 association with cyclin D and p21 mRNAs [80].
AUF1 Binding (association) of HuR
1) Confidence 0.06 Published 2010 Journal Cell Mol Life Sci Section Body Doc Link PMC2921490 Disease Relevance 0.38 Pain Relevance 0.16
Associations of KSRP and AUF1 p45, or KSRP and HuR, allow fine tuning of ARE-mRNA stability [93, 94].
AUF1 p45 Binding (Associations) of HuR
2) Confidence 0.06 Published 2010 Journal Cell Mol Life Sci Section Body Doc Link PMC2921490 Disease Relevance 0.36 Pain Relevance 0.14

General Comments

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