INT327333

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 3.74
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Fxr1) intracellular (TNF) extracellular matrix organization (TNF)
cytoplasm (Fxr1) extracellular space (TNF) signal transduction (TNF)
TNF (Homo sapiens)
Fxr1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory stimuli 9 82.84 Quite High
Inflammation 348 75.36 Quite High
cytokine 99 55.24 Quite High
cINOD 15 46.88 Quite Low
chemokine 30 5.00 Very Low Very Low Very Low
Arthritis 15 5.00 Very Low Very Low Very Low
Inflammatory response 12 5.00 Very Low Very Low Very Low
Kinase C 12 5.00 Very Low Very Low Very Low
aspirin 3 5.00 Very Low Very Low Very Low
Inflammatory mediators 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Intellectual Impairment 3 99.96 Very High Very High Very High
Cancer 432 95.80 Very High Very High Very High
Shock 3 94.88 High High
Starvation 6 93.68 High High
Frailty 3 93.16 High High
Targeted Disruption 18 92.04 High High
Bacterial Infection 3 86.80 High High
INFLAMMATION 360 82.52 Quite High
Colon Cancer 24 38.48 Quite Low
Hypoxia 33 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A recent review describes in detail the role of the miRNP (microribonucleoprotein)-associated proteins FXR1 and Argonaute 2 as effector molecules that bind the ARE to activate TNF-?
TNF Binding (bind) of FXR1
1) Confidence 0.06 Published 2010 Journal Cell Mol Life Sci Section Body Doc Link PMC2921490 Disease Relevance 1.28 Pain Relevance 0.15
The fragile X mental retardation, autosomal homolog 1 (FXR1), is a K–H type RNA-binding protein that interacts with TNF-?
TNF Binding (interacts) of autosomal homolog 1 associated with intellectual impairment
2) Confidence 0.06 Published 2010 Journal Cell Mol Life Sci Section Body Doc Link PMC2921490 Disease Relevance 1.23 Pain Relevance 0.17
The fragile X mental retardation, autosomal homolog 1 (FXR1), is a K–H type RNA-binding protein that interacts with TNF-?
TNF Binding (interacts) of FXR1 associated with intellectual impairment
3) Confidence 0.06 Published 2010 Journal Cell Mol Life Sci Section Body Doc Link PMC2921490 Disease Relevance 1.23 Pain Relevance 0.16

General Comments

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