INT327334

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.46
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il10, TNF) extracellular region (Il10, TNF) intracellular (Il10, TNF)
signal transduction (TNF) plasma membrane (TNF) extracellular matrix organization (TNF)
Il10 (Mus musculus)
TNF (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 116 100.00 Very High Very High Very High
cytokine 33 100.00 Very High Very High Very High
chemokine 10 5.00 Very Low Very Low Very Low
cINOD 5 5.00 Very Low Very Low Very Low
Arthritis 5 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
Kinase C 4 5.00 Very Low Very Low Very Low
Inflammatory stimuli 3 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 120 100.00 Very High Very High Very High
Cancer 144 93.64 High High
Chronic Disease 1 87.20 High High
Inflammatory Bowel Disease 4 85.20 High High
Breast Cancer 5 83.84 Quite High
Hepatocellular Cancer 2 64.76 Quite High
Immune System Diseases 1 48.24 Quite Low
Glioma 2 47.24 Quite Low
Colitis 6 46.88 Quite Low
Colon Cancer 8 45.92 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
An indirect involvement of TTP dysfunction in chronic inflammatory conditions may be deduced from the observation that the anti-inflammatory cytokine, IL-10, increases TTP expression and subsequently reduces the pro-inflammatory cytokines, TNF-?
IL-10 Negative_regulation (reduces) of TNF associated with inflammation and cytokine
1) Confidence 0.02 Published 2010 Journal Cell Mol Life Sci Section Body Doc Link PMC2921490 Disease Relevance 1.46 Pain Relevance 0.60

General Comments

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