INT327386

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Context Info
Confidence 0.20
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.98
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TNF, Oxtr) extracellular space (TNF) extracellular region (TNF)
plasma membrane (TNF) intracellular (TNF) extracellular matrix organization (TNF)
Anatomy Link Frequency
smooth muscle 2
TNF (Homo sapiens)
Oxtr (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 46 100.00 Very High Very High Very High
Inflammation 28 100.00 Very High Very High Very High
bradykinin 10 85.60 High High
agonist 18 84.32 Quite High
Inflammatory mediators 2 18.72 Low Low
Dismenorea 6 5.00 Very Low Very Low Very Low
corticosteroid 4 5.00 Very Low Very Low Very Low
Neuropeptide 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 30 100.00 Very High Very High Very High
Asthma 68 91.92 High High
Necrosis 6 71.00 Quite High
Cancer 8 70.64 Quite High
Disease 8 57.56 Quite High
Pyelonephritis 2 52.84 Quite High
Increased Venous Pressure Under Development 2 51.92 Quite High
Myocardial Infarction 2 51.04 Quite High
Respiratory Disease 2 20.08 Low Low
Nicotine Addiction 4 12.32 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Real time PCR was performed to assess whether oxytocin receptor expression was modulated by pro-inflammatory cytokines, TNF?
TNF Spec (whether) Regulation (modulated) of Spec (whether) Gene_expression (expression) of oxytocin receptor associated with inflammation and cytokine
1) Confidence 0.20 Published 2010 Journal Respir Res Section Body Doc Link PMC2922094 Disease Relevance 0.10 Pain Relevance 0.10
Here, we report the expression and function of oxytocin receptor in airway smooth muscle (both in human and mouse); more importantly, we also report that oxytocin receptor expression is affected by IL-13 and TNF?.
TNF Regulation (affected) of Gene_expression (expression) of oxytocin receptor in smooth muscle
2) Confidence 0.20 Published 2010 Journal Respir Res Section Body Doc Link PMC2922094 Disease Relevance 0.88 Pain Relevance 0.35

General Comments

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