INT327405

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Context Info
Confidence 0.42
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.30
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Lox, Ptk2) extracellular matrix organization (Ptk2) cytoplasm (Ptk2)
signal transducer activity (Ptk2) cytosol (Ptk2) extracellular region (Lox)
Lox (Mus musculus)
Ptk2 (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 3 76.80 Quite High
cytokine 3 63.36 Quite High
Bioavailability 2 50.72 Quite High
imagery 3 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 122 100.00 Very High Very High Very High
Death 5 96.36 Very High Very High Very High
Metastasis 50 93.12 High High
Adenocarcinoma 1 72.44 Quite High
Squamous Cell Carcinoma 9 71.48 Quite High
Adhesions 6 65.60 Quite High
Head & Neck Cancer 6 50.00 Quite Low
Toxicity 3 49.04 Quite Low
Severe Combined Immunodeficiency 11 42.52 Quite Low
Apoptosis 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recently Payne et al, have demonstrated that lysyl oxidase (LOX), a copper dependent kinase, promotes tumor cell migration and invasiveness via the activation of FAK [24].
LOX Positive_regulation (activation) of FAK associated with cancer
1) Confidence 0.42 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2922193 Disease Relevance 1.30 Pain Relevance 0.10

General Comments

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