INT327406

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Context Info
Confidence 0.23
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.62
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Lox, Lox, Ptk2) extracellular region (Lox, Lox) oxidoreductase activity (Lox, Lox)
proteinaceous extracellular matrix (Lox, Lox) extracellular matrix organization (Ptk2) cytoplasm (Ptk2)
Lox (Mus musculus)
Lox (Mus musculus)
Ptk2 (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 6 77.40 Quite High
cytokine 6 63.36 Quite High
Bioavailability 4 50.72 Quite High
imagery 6 5.00 Very Low Very Low Very Low
palliative 2 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 244 100.00 Very High Very High Very High
Death 10 96.96 Very High Very High Very High
Metastasis 100 93.72 High High
Adenocarcinoma 2 73.04 Quite High
Squamous Cell Carcinoma 18 72.08 Quite High
Adhesions 12 66.20 Quite High
Head & Neck Cancer 12 50.00 Quite Low
Toxicity 6 49.04 Quite Low
Severe Combined Immunodeficiency 22 43.12 Quite Low
Apoptosis 20 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recently Payne et al, have demonstrated that lysyl oxidase (LOX), a copper dependent kinase, promotes tumor cell migration and invasiveness via the activation of FAK [24].
lysyl oxidase Positive_regulation (promotes) of LOX Positive_regulation (activation) of FAK associated with cancer
1) Confidence 0.23 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2922193 Disease Relevance 1.31 Pain Relevance 0.10
Recently Payne et al, have demonstrated that lysyl oxidase (LOX), a copper dependent kinase, promotes tumor cell migration and invasiveness via the activation of FAK [24].
LOX Positive_regulation (promotes) of LOX Positive_regulation (activation) of FAK associated with cancer
2) Confidence 0.23 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2922193 Disease Relevance 1.30 Pain Relevance 0.10

General Comments

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