INT327446

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.30
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (PPIG) protein folding (PPIG) nucleoplasm (PPIG)
nucleolus (PPIG) nucleus (PPIG) cytoplasm (PPIG)
PPIG (Homo sapiens)
Pain Link Frequency Relevance Heat
Bile 3 85.04 High High
Bioavailability 6 78.32 Quite High
adenocard 1 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rhabdomyolysis 8 99.22 Very High Very High Very High
Myositis 1 98.82 Very High Very High Very High
Nephrotoxicity 1 98.62 Very High Very High Very High
Dyslipidemia /

Combined Dyslipidemia

24 50.00 Quite Low
Disorder Of Lipid Metabolism 78 5.00 Very Low Very Low Very Low
Cardiovascular Disease 35 5.00 Very Low Very Low Very Low
Diabetes Mellitus 25 5.00 Very Low Very Low Very Low
Coronary Artery Disease 11 5.00 Very Low Very Low Very Low
Hyperlipidemia 10 5.00 Very Low Very Low Very Low
Metabolic Syndrome 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interaction with cyclosporine has been reported to increase the risk of nephrotoxicity, myositis, and rhabdomyolysis, partly due to the fact that both are metabolized through CYP 3A4.37 Careful consideration should be given when fenofibric acid is administered with other potential nephrotoxic drugs and, if necessary, lower doses of fenofibric acid may be used.21
Positive_regulation (through) of Localization (metabolized) of CYP associated with nephrotoxicity, rhabdomyolysis and myositis
1) Confidence 0.07 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2922314 Disease Relevance 0.30 Pain Relevance 0.12

General Comments

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