INT327507

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.58
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

structural constituent of ribosome (CYLD) ribosome (CYLD) intracellular (CYLD)
cytoplasm (CYLD) cytosol (CYLD) peptidase activity (CYLD)
Anatomy Link Frequency
liver 2
CYLD (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 5 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
headache 3 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Neurobehavioral 1 5.00 Very Low Very Low Very Low
Neuritis 1 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatotoxicity 8 99.90 Very High Very High Very High
Stress 29 85.96 High High
Poisoning 32 82.72 Quite High
Syndrome 1 54.00 Quite High
Cancer 10 43.76 Quite Low
Toxicity 55 39.12 Quite Low
Emergencies 2 35.36 Quite Low
Iron Overload 10 5.00 Very Low Very Low Very Low
Lead Poisoning 8 5.00 Very Low Very Low Very Low
Disease 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NAC besides preventing hepatotoxicity and reducing the rate of CdMT release from the liver, protect directly by forming a complex with Cd [135], or indirectly by scavenging free radicals [136] or by serving as a cysteine donor for GSH synthesis.


Negative_regulation (reducing) of Localization (release) of CdMT in liver associated with hepatotoxicity
1) Confidence 0.05 Published 2010 Journal International Journal of Environmental Research and Public Health Section Body Doc Link PMC2922724 Disease Relevance 0.58 Pain Relevance 0

General Comments

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