INT327691

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Context Info
Confidence 0.37
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.33
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Comt) methyltransferase activity (Comt) plasma membrane (Comt)
Comt (Mus musculus)
Pain Link Frequency Relevance Heat
Catechol-O-methyltransferase 27 93.36 High High
Dopamine 15 92.36 High High
Hippocampus 9 38.96 Quite Low
Nucleus accumbens 5 5.00 Very Low Very Low Very Low
Neurotransmitter 5 5.00 Very Low Very Low Very Low
Catecholamine 4 5.00 Very Low Very Low Very Low
dopamine receptor 3 5.00 Very Low Very Low Very Low
Ventral tegmentum 2 5.00 Very Low Very Low Very Low
gABA 2 5.00 Very Low Very Low Very Low
monoamine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aggression 2 96.40 Very High Very High Very High
Cognitive Disorder 6 94.56 High High
Sprains And Strains 57 84.56 Quite High
Disease 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Dislocations 1 5.00 Very Low Very Low Very Low
Schizophrenia 1 5.00 Very Low Very Low Very Low
Anxiety Disorder 1 5.00 Very Low Very Low Very Low
Manic Depressive Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This study identifies the key sequence variant that leads to differences in Comt mRNA and protein levels among mice, and that modulates synaptic function and pharmacological and behavioral traits.


Negative_regulation (differences) of Transcription (levels) of Comt
1) Confidence 0.37 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2923157 Disease Relevance 0.33 Pain Relevance 0.18

General Comments

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