INT327712

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.27
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Comt) methyltransferase activity (Comt) mRNA processing (Rbm39)
RNA binding (Rbm39) nucleus (Rbm39) plasma membrane (Comt)
Anatomy Link Frequency
nucleus accumbens 1
ventral 1
Comt (Mus musculus)
Rbm39 (Mus musculus)
Pain Link Frequency Relevance Heat
dopamine receptor 6 100.00 Very High Very High Very High
Nucleus accumbens 10 98.84 Very High Very High Very High
Ventral tegmentum 4 98.08 Very High Very High Very High
antagonist 4 82.80 Quite High
gABA 4 76.56 Quite High
Catechol-O-methyltransferase 54 72.64 Quite High
Hippocampus 18 64.36 Quite High
Dopamine 30 5.00 Very Low Very Low Very Low
Neurotransmitter 10 5.00 Very Low Very Low Very Low
Catecholamine 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sprains And Strains 114 69.44 Quite High
Cognitive Disorder 12 5.00 Very Low Very Low Very Low
Disease 8 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Aggression 4 5.00 Very Low Very Low Very Low
Stress 4 5.00 Very Low Very Low Very Low
Dislocations 2 5.00 Very Low Very Low Very Low
Schizophrenia 2 5.00 Very Low Very Low Very Low
Anxiety Disorder 2 5.00 Very Low Very Low Very Low
Manic Depressive Disorder 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Twelve classical phenotypes with high content validity map to the Comt locus (p<0.02, Table S2), including binding affinity of both dopamine receptors (DRD1 and DRD2) in caudate, nucleus accumbens, ventral tegmental area, and prefrontal cortex [19].
Comt Binding (affinity) of receptors in nucleus accumbens associated with ventral tegmentum, nucleus accumbens and dopamine receptor
1) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2923157 Disease Relevance 0.13 Pain Relevance 0.37
Twelve classical phenotypes with high content validity map to the Comt locus (p<0.02, Table S2), including binding affinity of both dopamine receptors (DRD1 and DRD2) in caudate, nucleus accumbens, ventral tegmental area, and prefrontal cortex [19].
Comt Binding (affinity) of receptors in ventral associated with ventral tegmentum, nucleus accumbens and dopamine receptor
2) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2923157 Disease Relevance 0.13 Pain Relevance 0.37

General Comments

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