INT327728

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Context Info
Confidence 0.27
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.73
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Notch1) Golgi apparatus (Notch1) plasma membrane (Notch1)
nucleus (Notch1) embryo development (Notch1) cytoplasm (Notch1)
Anatomy Link Frequency
notch 2
Notch1 (Mus musculus)
Pain Link Frequency Relevance Heat
withdrawal 1 78.20 Quite High
tolerance 4 66.28 Quite High
cytokine 11 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 33 99.56 Very High Very High Very High
Death 7 94.52 High High
Apoptosis 44 73.68 Quite High
Severe Combined Immunodeficiency 11 50.00 Quite Low
Targeted Disruption 1 28.44 Quite Low
Adhesions 3 5.00 Very Low Very Low Very Low
Hematological Disease 3 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 2 5.00 Very Low Very Low Very Low
Infection 2 5.00 Very Low Very Low Very Low
Infarction 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our observation of the up regulation of gene expression of the notch receptor and its ligand jagged 1 suggested that the addition of these two compounds during expansion, activated the notch signalling molecules.
Regulation (regulation) of Gene_expression (expression) of notch receptor in notch
1) Confidence 0.27 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2923186 Disease Relevance 0.07 Pain Relevance 0.04
Our present results provide important insights into the regulation of Notch1 expression under the stress condition, and into periostin as a regulator of Notch1 expression, which is another unidentified function of periostin.


Regulation (regulation) of Gene_expression (expression) of Notch1 associated with stress
2) Confidence 0.26 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2923609 Disease Relevance 0.65 Pain Relevance 0.03

General Comments

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