INT327782

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Context Info
Confidence 0.36
First Reported 2010
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.63
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transmembrane transporter activity (AQP1) plasma membrane (AQP1) nucleus (AQP1)
transmembrane transport (AQP1) cytoplasm (AQP1)
Anatomy Link Frequency
astrocytes 4
AQP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cerebral cortex 4 40.52 Quite Low
Substantia nigra 4 37.20 Quite Low
Dopamine 16 21.28 Low Low
Spinal cord 20 5.00 Very Low Very Low Very Low
Multiple sclerosis 12 5.00 Very Low Very Low Very Low
Inflammation 10 5.00 Very Low Very Low Very Low
Demyelination 8 5.00 Very Low Very Low Very Low
potassium channel 6 5.00 Very Low Very Low Very Low
Neuritis 6 5.00 Very Low Very Low Very Low
addiction 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 138 97.92 Very High Very High Very High
Congenital Anomalies 4 94.16 High High
Neurodegenerative Disease 26 48.32 Quite Low
Movement Disorders 2 46.88 Quite Low
Parkinson's Disease 2 31.04 Quite Low
Neuromyelitis Optica 114 5.00 Very Low Very Low Very Low
Motor Neuron Diseases 38 5.00 Very Low Very Low Very Low
Demyelinating Disease 28 5.00 Very Low Very Low Very Low
Targeted Disruption 22 5.00 Very Low Very Low Very Low
Creutzfeldt Jakob Disease 20 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, treatment with hydrogen peroxide did not affect the levels of AQP1 protein expression in human astrocytes culture, suggesting that these stimuli do not directly up-regulate AQP1 expression in astrocytes.
Neg (not) Regulation (regulate) of Gene_expression (expression) of AQP1 in astrocytes
1) Confidence 0.36 Published 2010 Journal Current Neuropharmacology Section Body Doc Link PMC2923365 Disease Relevance 0.88 Pain Relevance 0
However, treatment with hydrogen peroxide did not affect the levels of AQP1 protein expression in human astrocytes culture, suggesting that these stimuli do not directly up-regulate AQP1 expression in astrocytes.
Neg (not) Regulation (affect) of Gene_expression (expression) of AQP1 in astrocytes
2) Confidence 0.36 Published 2010 Journal Current Neuropharmacology Section Body Doc Link PMC2923365 Disease Relevance 0.76 Pain Relevance 0

General Comments

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