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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.32
Pain Relevance 0.85

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cnp) plasma membrane (Cnp) intracellular (Cnp)
kinase activity (Cnp) cytoplasm (Cnp)
Anatomy Link Frequency
spinal cords 1
Cnp (Mus musculus)
Pain Link Frequency Relevance Heat
Neuropathic pain 8 100.00 Very High Very High Very High
Inflammation 5 98.60 Very High Very High Very High
metalloproteinase 29 97.92 Very High Very High Very High
Nerve growth factor 7 79.08 Quite High
Pain 30 78.08 Quite High
Eae 9 46.12 Quite Low
Spinal cord 15 43.44 Quite Low
Sciatica 1 42.64 Quite Low
allodynia 3 33.28 Quite Low
Acute pain 2 29.40 Quite Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 14 100.00 Very High Very High Very High
INFLAMMATION 7 98.60 Very High Very High Very High
Injury 21 88.16 High High
Syndrome 1 85.04 High High
Pain 33 78.08 Quite High
Coagulation Disorder 9 74.08 Quite High
Pressure And Volume Under Development 13 50.24 Quite High
Nerve Root Compression 1 42.64 Quite Low
Nociception 11 28.44 Quite Low
Hemorrhage 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
DNA microarray analysis showed significantly increased expression of a number of genes associated with inflammation and astrocytic activation in the spinal cords of rats that developed CNP. mRNA levels of glial fibrilary acidic protein (GFAP) and AQP4 significantly increased in CNP spinal cords of rats.
Transcription (levels) of CNP in spinal cords associated with inflammation and neuropathic pain
1) Confidence 0.09 Published 2010 Journal Current Neuropharmacology Section Body Doc Link PMC2923366 Disease Relevance 1.25 Pain Relevance 0.68
The proportion of BPP/CNP transcripts in B. alternatus was similar to B. atrox and B. jararaca but about half that of B. insularis, while serine proteinases and C-type lectins were generally less abundant than in other Bothrops species.
Transcription (transcripts) of CNP
2) Confidence 0.03 Published 2010 Journal BMC Genomics Section Body Doc Link PMC3017861 Disease Relevance 0.07 Pain Relevance 0.17

General Comments

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