INT327893

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Context Info
Confidence 0.21
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.09
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CNTNAP1) cell adhesion (CNTNAP1) cytoskeleton organization (CNTNAP1)
CNTNAP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Spinal cord 16 56.56 Quite High
allodynia 9 5.00 Very Low Very Low Very Low
Peripheral nervous system 3 5.00 Very Low Very Low Very Low
Demyelination 3 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Buprenorphine 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
unmyelinated 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Spinal Cord Injury 70 86.80 High High
Injury 47 50.00 Quite Low
Severe Combined Immunodeficiency 27 50.00 Quite Low
Cicatrix 26 29.92 Quite Low
Neuropathic Pain 9 5.00 Very Low Very Low Very Low
Cancer 8 5.00 Very Low Very Low Very Low
Sprains And Strains 4 5.00 Very Low Very Low Very Low
Demyelinating Disease 3 5.00 Very Low Very Low Very Low
Contusions 3 5.00 Very Low Very Low Very Low
Paralysis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CASPR is highly localized to the paranodal region of myelinated axons and can be used as an index of myelin integrity [42], [43], [44]; previous studies have demonstrated that CASPR has a compact paranodal restricted staining pattern in uninjured axons (Fig. 6A arrows) and this compact pattern becomes more diffusely distributed along the axon following SCI (Fig. 6A arrowheads) [43].
Localization (localized) of CASPR associated with spinal cord injury
1) Confidence 0.21 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2923623 Disease Relevance 0.09 Pain Relevance 0.03

General Comments

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