INT327980

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Context Info
Confidence 0.15
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.89
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TNFRSF11A) extracellular space (PNLIP) small molecule metabolic process (PNLIP)
extracellular region (PNLIP) cell-cell signaling (TNFRSF11A) lipid metabolic process (PNLIP)
PNLIP (Homo sapiens)
TNFRSF11A (Homo sapiens)
Pain Link Frequency Relevance Heat
Migraine 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatic Cancer 21 83.88 Quite High
Apoptosis 34 80.88 Quite High
Cancer 14 78.72 Quite High
Solid Tumor 1 76.92 Quite High
Aggression 2 75.48 Quite High
Injury 10 5.00 Very Low Very Low Very Low
Metastasis 2 5.00 Very Low Very Low Very Low
Parkinson's Disease 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Adenocarcinoma 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Studies have shown that PTL targets NF-kB via inhibition of the upstream regulator IkB kinase (IKK) [17] which phosphorylates IkB and targets it for proteasomal degradation.
PTL Regulation (targets) of NF-kB
1) Confidence 0.15 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2924280 Disease Relevance 0.89 Pain Relevance 0

General Comments

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