INT327991

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Context Info
Confidence 0.26
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.20
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (TRPV1, ROS1) cell differentiation (ROS1) cell proliferation (ROS1)
cytosol (TRPV1) transport (TRPV1) lipid metabolic process (TRPV1)
TRPV1 (Homo sapiens)
ROS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 11 86.32 High High
imagery 14 83.12 Quite High
agonist 8 80.52 Quite High
Glutamate 1 77.76 Quite High
Inflammatory mediators 3 75.48 Quite High
Inflammation 41 73.24 Quite High
qutenza 13 67.48 Quite High
Spinal cord 21 50.36 Quite High
Pain 6 19.92 Low Low
Dorsal horn 4 18.52 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 34 75.08 Quite High
Arthritis 22 73.24 Quite High
Nociception 15 52.56 Quite High
Pain 7 19.92 Low Low
Hyperalgesia 6 5.00 Very Low Very Low Very Low
Neuropathic Pain 4 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low
Osteoarthritis 3 5.00 Very Low Very Low Very Low
Arthropathy 3 5.00 Very Low Very Low Very Low
Neurogenic Inflammation 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The TRPV1 activation of the SW982 cells produced a statistically significant 1.68-fold increase in extracellular ROS metabolite 2, 5-DHBA (7.8 ± 0.9 pg/ml, p < 0.05) compared to control cells treated with the vehicle (4.6 ± 0.4 pg/ml).


Positive_regulation (activation) of TRPV1 Positive_regulation (increase) of ROS
1) Confidence 0.26 Published 2010 Journal Mol Pain Section Body Doc Link PMC2924298 Disease Relevance 0.20 Pain Relevance 0.40

General Comments

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