INT327992

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Context Info
Confidence 0.28
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.35
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (TRPV1, ROS1) cell differentiation (ROS1) cell proliferation (ROS1)
cytosol (TRPV1) transport (TRPV1) lipid metabolic process (TRPV1)
TRPV1 (Homo sapiens)
ROS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 11 99.20 Very High Very High Very High
Inflammation 41 94.24 High High
qutenza 13 94.08 High High
agonist 8 93.68 High High
imagery 14 86.20 High High
Lasting pain 1 58.52 Quite High
central sensitization 5 57.44 Quite High
methotrexate 2 47.44 Quite Low
cytokine 2 44.80 Quite Low
substance P 1 41.00 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 34 94.24 High High
Pain 7 58.52 Quite High
Nociception 15 51.72 Quite High
Fever 2 45.24 Quite Low
Pressure And Volume Under Development 1 42.96 Quite Low
Arthritis 22 37.44 Quite Low
Targeted Disruption 2 29.28 Quite Low
Rheumatoid Arthritis 1 28.24 Quite Low
Osteoarthritis 3 9.44 Low Low
Hyperalgesia 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These enhanced ROS responses were blocked by a TRPV1 antagonist or ROS scavenger, PBN, indicating that ROS generation in synoviocytes is TRPV1 mediated in the experimental conditions utilized.


TRPV1 Positive_regulation (mediated) of Gene_expression (generation) of ROS associated with antagonist
1) Confidence 0.28 Published 2010 Journal Mol Pain Section Body Doc Link PMC2924298 Disease Relevance 0.35 Pain Relevance 0.60

General Comments

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