INT328146

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Context Info
Confidence 0.48
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.99
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ube3a) transport (Gabrb3) nucleus (Ube3a)
plasma membrane (Gabrb3) ligase activity (Ube3a)
Gabrb3 (Mus musculus)
Ube3a (Mus musculus)
Pain Link Frequency Relevance Heat
Electroencephalography 14 73.72 Quite High
Neurobehavioral 1 68.88 Quite High
Hippocampus 7 5.00 Very Low Very Low Very Low
cerebral cortex 6 5.00 Very Low Very Low Very Low
Eae 3 5.00 Very Low Very Low Very Low
long-term potentiation 1 5.00 Very Low Very Low Very Low
GABA receptor 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Angelman Syndrome 55 93.80 High High
Cleft Palate 7 90.64 High High
Uniparental Disomy 8 84.00 Quite High
Autism 12 77.40 Quite High
Epilepsy 5 74.84 Quite High
Congenital Anomalies 4 74.32 Quite High
Intellectual Impairment 2 70.64 Quite High
Convulsion 12 52.16 Quite High
Anxiety Disorder 20 40.40 Quite Low
Stress 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Using a chromosomal engineering strategy, we generated mutant mice with a 1.6-Mb chromosomal deletion from Ube3a to Gabrb3, which inactivated the Ube3a and Gabrb3 genes and deleted the Atp10a gene.
Gabrb3 Negative_regulation (inactivated) of Ube3a
1) Confidence 0.48 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2924885 Disease Relevance 0.99 Pain Relevance 0.11

General Comments

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