INT328223

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.69
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Mmp14, Mmp13) extracellular space (Mmp13) extracellular region (Mmp13)
Golgi apparatus (Mmp13) proteinaceous extracellular matrix (Mmp13) lysosome (Mmp13)
Mmp14 (Mus musculus)
Mmp13 (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 30 98.76 Very High Very High Very High
Osteoarthritis 1 94.24 High High
metalloproteinase 7 83.52 Quite High
Inflammation 14 45.68 Quite Low
Pain 1 41.44 Quite Low
Arthritis 33 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 30 98.76 Very High Very High Very High
Targeted Disruption 1 96.96 Very High Very High Very High
Frailty 2 94.24 High High
Disease 5 57.60 Quite High
INFLAMMATION 14 45.68 Quite Low
Synovitis 1 44.64 Quite Low
Syndrome 1 43.40 Quite Low
Arthralgia 1 41.68 Quite Low
Severe Combined Immunodeficiency 14 5.96 Low Low
Arthritis 34 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In vivo, MMP-14 (MT1-MMP) and MMP-2 (gelatinase A) are two of several enzymes responsible for the activation of proMMP-13 and both are overexpressed in RA.
MMP-14 Regulation (responsible) of Positive_regulation (activation) of proMMP-13 associated with rheumatoid arthritis
1) Confidence 0.07 Published 2010 Journal Annals of the Rheumatic Diseases Section Body Doc Link PMC2925150 Disease Relevance 0.69 Pain Relevance 0.29

General Comments

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