INT328224

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.80
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Col2a1, Mmp13) extracellular region (Col2a1, Mmp13) proteinaceous extracellular matrix (Col2a1, Mmp13)
peptidase activity (Mmp13) Golgi apparatus (Mmp13) lysosome (Mmp13)
Col2a1 (Mus musculus)
Mmp13 (Mus musculus)
Pain Link Frequency Relevance Heat
Arthritis 33 92.00 High High
rheumatoid arthritis 30 88.88 High High
Inflammation 14 75.04 Quite High
metalloproteinase 7 5.00 Very Low Very Low Very Low
Osteoarthritis 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arthritis 34 92.00 High High
Rheumatoid Arthritis 30 88.88 High High
Severe Combined Immunodeficiency 14 84.48 Quite High
INFLAMMATION 14 75.04 Quite High
Disease 5 37.60 Quite Low
Frailty 2 5.00 Very Low Very Low Very Low
Immunization 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Syndrome 1 5.00 Very Low Very Low Very Low
Arthralgia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cleaved fragments of collagen type II again can further induce MMP-13 gene expression and result in a cycle of collagen degradation.
collagen type II Positive_regulation (induce) of Gene_expression (expression) of MMP-13
1) Confidence 0.04 Published 2010 Journal Annals of the Rheumatic Diseases Section Body Doc Link PMC2925150 Disease Relevance 0.80 Pain Relevance 0.29

General Comments

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