INT328286

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 2
Disease Relevance 2.93
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (C1orf38)
C1orf38 (Homo sapiens)
Pain Link Frequency Relevance Heat
bradykinin 8 99.46 Very High Very High Very High
abdominal pain 6 93.96 High High
antagonist 4 65.24 Quite High
Disease Link Frequency Relevance Heat
Pressure And Volume Under Development 172 99.64 Very High Very High Very High
Abdominal Pain 6 93.96 High High
Urticaria 4 90.00 High High
Lymphoproliferative Disease 6 83.96 Quite High
Recurrence 10 73.12 Quite High
Hereditary Angioedema 2 71.16 Quite High
Disease 20 56.36 Quite High
Syndrome 2 48.36 Quite Low
Lymphatic System Cancer 16 5.00 Very Low Very Low Very Low
Laryngeal Edema 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This could be anticipated based on the fact that in both forms angioedema is mediated by bradykinin episodically released by inappropriate activation of the contact-kinin system lacking its major physiologic regulator C1-INH [6,7].
Positive_regulation (activation) of contact-kinin associated with pressure and volume under development and bradykinin
1) Confidence 0.01 Published 2010 Journal Allergy Asthma Clin Immunol Section Body Doc Link PMC2925362 Disease Relevance 1.39 Pain Relevance 0.12
Acquired angioedema

Acquired angioedema (AAE) is characterized by acquired deficiency of C1 inhibitor (C1-INH), hyperactivation of the classical pathway of human complement and angioedema symptoms mediated by bradykinin released by inappropriate activation of the contact-kinin system.

Positive_regulation (activation) of contact-kinin associated with pressure and volume under development and bradykinin
2) Confidence 0.01 Published 2010 Journal Allergy Asthma Clin Immunol Section Title Doc Link PMC2925362 Disease Relevance 1.54 Pain Relevance 0.21

General Comments

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