INT328304

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.22
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (POMC, CRH) signal transduction (POMC, CRH) extracellular region (POMC, CRH)
small molecule metabolic process (POMC) response to stress (CRH) cell-cell signaling (POMC)
POMC (Homo sapiens)
CRH (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 19 65.04 Quite High
agonist 17 5.00 Very Low Very Low Very Low
Inflammation 10 5.00 Very Low Very Low Very Low
Somatostatin 7 5.00 Very Low Very Low Very Low
medulla 4 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
tolerance 4 5.00 Very Low Very Low Very Low
Neuropeptide 3 5.00 Very Low Very Low Very Low
vagus nerve 3 5.00 Very Low Very Low Very Low
Eae 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Growth Problems 5 80.80 Quite High
Aging 3 74.72 Quite High
Obesity 15 64.08 Quite High
Targeted Disruption 17 5.00 Very Low Very Low Very Low
Appetite Loss 13 5.00 Very Low Very Low Very Low
INFLAMMATION 12 5.00 Very Low Very Low Very Low
Stress 10 5.00 Very Low Very Low Very Low
Apoptosis 8 5.00 Very Low Very Low Very Low
Cancer 6 5.00 Very Low Very Low Very Low
Repression 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The last observation is significant, because higher doses of ghrelin/GHS evoke ACTH, cortisol, and prolactin secretion acutely in humans and animals, putatively by inducing hypothalamic secretion of one or both primary ACTH-releasing peptides, corticotrophin-releasing hormone (CRH), and arginine vasopressin (AVP) [272, 274–278].
ACTH Positive_regulation (inducing) of Localization (secretion) of CRH
1) Confidence 0.07 Published 2010 Journal International Journal of Peptides Section Body Doc Link PMC2925380 Disease Relevance 0.22 Pain Relevance 0.03

General Comments

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