INT328308

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (CRH, KISS1) signal transduction (CRH) extracellular space (CRH)
cytoskeleton organization (KISS1) response to stress (CRH)
CRH (Homo sapiens)
KISS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Neuropeptide 3 99.66 Very High Very High Very High
antagonist 19 5.00 Very Low Very Low Very Low
agonist 17 5.00 Very Low Very Low Very Low
Inflammation 10 5.00 Very Low Very Low Very Low
Somatostatin 7 5.00 Very Low Very Low Very Low
medulla 4 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
tolerance 4 5.00 Very Low Very Low Very Low
vagus nerve 3 5.00 Very Low Very Low Very Low
Eae 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Birth Weight 1 41.68 Quite Low
Neuroendocrine Cancer 1 41.20 Quite Low
Placental Insufficiency 1 40.96 Quite Low
Cancer 6 35.36 Quite Low
Carcinoid 1 31.36 Quite Low
Pituitary Cancer 1 30.32 Quite Low
Carcinoma 3 28.40 Quite Low
Fetal Weight 1 17.40 Low Low
Targeted Disruption 17 5.00 Very Low Very Low Very Low
Obesity 15 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The mechanism may involve neuropeptide Y (Y1 or Y5) or CRH-dependent inhibition of kisspeptin, which together supervise gonadotropin-releasing hormone secretion, and thereby pulsatile LH secretion [622, 624–627].
CRH Negative_regulation (inhibition) of kisspeptin associated with neuropeptide
1) Confidence 0.02 Published 2010 Journal International Journal of Peptides Section Body Doc Link PMC2925380 Disease Relevance 0 Pain Relevance 0.05

General Comments

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