INT328384

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.93
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ghrl, ALPL) extracellular region (Ghrl) plasma membrane (ALPL)
cytoplasm (Ghrl)
Anatomy Link Frequency
osteoblast 1
Ghrl (Rattus norvegicus)
ALPL (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 19 82.56 Quite High
Inflammation 10 55.04 Quite High
cytokine 4 54.00 Quite High
Pain 1 34.64 Quite Low
agonist 17 5.00 Very Low Very Low Very Low
Somatostatin 7 5.00 Very Low Very Low Very Low
medulla 4 5.00 Very Low Very Low Very Low
tolerance 4 5.00 Very Low Very Low Very Low
Neuropeptide 3 5.00 Very Low Very Low Very Low
vagus nerve 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoporosis 3 100.00 Very High Very High Very High
Apoptosis 8 99.00 Very High Very High Very High
Hypoglycemia 4 85.96 High High
Obesity 15 79.40 Quite High
Hyperglycemia 1 73.32 Quite High
Stress 10 72.16 Quite High
INFLAMMATION 12 55.04 Quite High
Cancer 6 52.80 Quite High
Necrosis 2 52.32 Quite High
Targeted Disruption 17 47.36 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Acylated and unacylated ghrelin stimulate osteoblast proliferation and differentiation, increase osteoblastic markers like osteocalcin and bone alkaline phosphatase, and repress osteoblast apoptosis putatively via phosphatidylinositol 3-kinase and mitogen-activated protein kinase signaling [566].
ghrelin Positive_regulation (increase) of bone alkaline phosphatase in osteoblast associated with osteoporosis and apoptosis
1) Confidence 0.01 Published 2010 Journal International Journal of Peptides Section Body Doc Link PMC2925380 Disease Relevance 0.93 Pain Relevance 0.13

General Comments

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