INT328421

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.67
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

hydrolase activity, acting on glycosyl bonds (Neu1) plasma membrane (Neu1) lysosome (Neu1)
Anatomy Link Frequency
lens 1
Neu1 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 1 98.56 Very High Very High Very High
Cataract 48 97.44 Very High Very High Very High
Aging 4 15.12 Low Low
Aids-related Complex 9 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Sprains And Strains 1 5.00 Very Low Very Low Very Low
Burns 1 5.00 Very Low Very Low Very Low
Alopecia 1 5.00 Very Low Very Low Very Low
Dislocations 1 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Importantly, the degradation of DNA in differentiating lens fibers requires the lysosomal enzyme, DNase II beta (DLAD), and in DLAD knock out mice nuclei are not degraded, resulting in lens opacity and cataract formation [10,11,69-71].
Protein_catabolism (degradation) of lysosomal enzyme in lens associated with targeted disruption and cataract
1) Confidence 0.02 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2925908 Disease Relevance 0.67 Pain Relevance 0

General Comments

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