INT328424

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Context Info
Confidence 0.21
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.34
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ros1) cell proliferation (Ros1) signal transduction (Ros1)
plasma membrane (Ros1) kinase activity (Ros1)
Anatomy Link Frequency
lenses 3
lec (Mus musculus)
Ros1 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cataract 48 96.80 Very High Very High Very High
Aids-related Complex 9 88.72 High High
Stress 2 29.64 Quite Low
Aging 4 5.00 Very Low Very Low Very Low
Sprains And Strains 1 5.00 Very Low Very Low Very Low
Burns 1 5.00 Very Low Very Low Very Low
Alopecia 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Dislocations 1 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study, X- irradiated lenses and control lenses are compared as a function of time for the 4 changes we previously observed in old lenses: 1) LEC loss, 2) decreased ability to degrade DNA in secondary lens fibers, 3) excessive ROS accumulation and ROS damage in the cortex, and 4) appearance of increasing opacities eventuating in cataracts.


Negative_regulation (loss) of LEC in lenses Negative_regulation (decreased) of Positive_regulation (accumulation) of ROS in lenses associated with cataract
1) Confidence 0.21 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2925908 Disease Relevance 0.34 Pain Relevance 0

General Comments

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