INT328431

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Context Info
Confidence 0.22
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.29
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (PIK3CD) cytoplasm (VEGFA) signal transduction (PIK3CD)
extracellular space (VEGFA) extracellular region (VEGFA) growth (VEGFA)
PIK3CD (Homo sapiens)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 1 46.40 Quite Low
Potency 2 7.92 Low Low
aspirin 2 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
IPN 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sarcoma 1 99.60 Very High Very High Very High
Fibrosarcoma 8 76.32 Quite High
Cancer 13 56.28 Quite High
Disease 1 5.60 Low Low
Thrombosis 1 5.00 Very Low Very Low Very Low
Hypoxia 1 5.00 Very Low Very Low Very Low
Solid Tumor 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Wound Healing 1 5.00 Very Low Very Low Very Low
Hypersensitivity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A PI3K inhibitor LY294002 significantly suppressed AKT phosphorylation and VEGF expression, which is similar to PO treatment, implying that PI3K is related to and downstream of VEGF in the cells.
PI3K Negative_regulation (suppressed) of Gene_expression (expression) of VEGF
1) Confidence 0.22 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2925949 Disease Relevance 0.29 Pain Relevance 0

General Comments

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