INT328433

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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.29
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (PRB4, VEGFA) extracellular space (VEGFA) growth (VEGFA)
proteinaceous extracellular matrix (VEGFA) molecular_function (PRB4) cytoplasm (VEGFA)
Anatomy Link Frequency
HT-1080 1
PRB4 (Homo sapiens)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 1 93.80 High High
aspirin 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
IPN 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fibrosarcoma 8 85.04 High High
Cancer 13 62.40 Quite High
Thrombosis 1 5.00 Very Low Very Low Very Low
Sarcoma 1 5.00 Very Low Very Low Very Low
Hypoxia 1 5.00 Very Low Very Low Very Low
Solid Tumor 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Wound Healing 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low
Hypersensitivity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Taken together, these results suggest that PO inhibits bFGF-induced angiogenesis in HUVECs and decreased the levels of PI3K, phospho-AKT and VEGF in HT-1080 cells.



PO Negative_regulation (decreased) of VEGF in HT-1080
1) Confidence 0.09 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2925949 Disease Relevance 0.29 Pain Relevance 0.05

General Comments

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