INT328435

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Context Info
Confidence 0.23
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.64
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (PIK3CD) cytoplasm (VEGFA) signal transduction (PIK3CD)
extracellular space (VEGFA) extracellular region (VEGFA) growth (VEGFA)
Anatomy Link Frequency
endothelial cells 2
PIK3CD (Homo sapiens)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 2 64.88 Quite High
IPN 1 60.96 Quite High
Potency 2 49.92 Quite Low
addiction 1 47.40 Quite Low
cytokine 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 13 99.78 Very High Very High Very High
Malignant Neoplastic Disease 1 99.22 Very High Very High Very High
Hypoxia 1 88.08 High High
Pathologic Neovascularization 1 65.28 Quite High
Inflammatory Pain 1 60.96 Quite High
Fibrosarcoma 8 50.00 Quite Low
Solid Tumor 1 48.00 Quite Low
Wound Healing 1 42.16 Quite Low
Thrombosis 1 5.00 Very Low Very Low Very Low
Sarcoma 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interruptions of one or more steps in these processes can negatively affect angiogenesis and inhibit early malignant lesions to lower the cancer risk [10] VEGF expression is mediated by the phosphoinositide 3-kinase (PI3K) pathway in endothelial cells [11].
PI3K Positive_regulation (mediated) of Gene_expression (expression) of VEGF in endothelial cells associated with malignant neoplastic disease and cancer
1) Confidence 0.23 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2925949 Disease Relevance 0.64 Pain Relevance 0.09

General Comments

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