INT328446

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Context Info
Confidence 0.16
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.68
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (PRB4) molecular_function (PRB4) biological_process (PRB4)
Anatomy Link Frequency
HT-1080 1
PRB4 (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 2 99.52 Very High Very High Very High
cva 2 54.36 Quite High
aspirin 4 5.00 Very Low Very Low Very Low
Potency 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
IPN 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fibrosarcoma 16 90.28 High High
Cancer 26 81.64 Quite High
Hemorrhage 2 54.36 Quite High
Thrombosis 2 53.76 Quite High
Sarcoma 2 5.00 Very Low Very Low Very Low
Hypoxia 2 5.00 Very Low Very Low Very Low
Solid Tumor 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Wound Healing 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As shown in Fig. 5C, PO at 12.5 µg/ml led to the decreased expression of PI3K and phosphorylation of its downstream target AKT.
Phosphorylation (phosphorylation) of PO
1) Confidence 0.16 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2925949 Disease Relevance 0.38 Pain Relevance 0.03
Consistently, immunefluorescence imaging analysis revealed that PO treatment attenuated AKT phosphorylation in HT-1080 cells.


Phosphorylation (phosphorylation) of PO in HT-1080 associated with imagery
2) Confidence 0.14 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2925949 Disease Relevance 0.30 Pain Relevance 0.05

General Comments

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