INT328507

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Context Info
Confidence 0.58
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.


Pain Term Frequency Confidence Heat
Migraine 4 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Clonidine 1 5.00 Very Low Very Low Very Low
cocaine 1 5.00 Very Low Very Low Very Low
antiepileptic Drug 7 5.00 Very Low Very Low Very Low
anticonvulsant 2 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
gABA 6 5.00 Very Low Very Low Very Low
Dopamine 1 5.00 Very Low Very Low Very Low
Substantia nigra 1 5.00 Very Low Very Low Very Low
Disease Term Frequency Confidence Heat
Breast Cancer 5 74.96 Quite High
Toxicity 8 50.00 Quite Low
Apoptosis 15 40.04 Quite Low
Fibrosis 1 5.00 Very Low Very Low Very Low
Hyperhomocysteinemia 5 5.00 Very Low Very Low Very Low
Alopecia 3 5.00 Very Low Very Low Very Low
Thrombocytopenia 6 5.00 Very Low Very Low Very Low
Tremor 1 5.00 Very Low Very Low Very Low
Abdominal Pain 1 5.00 Very Low Very Low Very Low
Depression 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, it has been shown that valproic acid downregulates expression of proteins essential for chromatin maintenance: SMCs 1-6 (Structural Maintenance of chromatin 1 to 6), DNMT1 (DNA methyl transferase-1), and HP1 (Heterochromatin Protein-1) [25].
Gene_expression (expression) of SMCs 1-6
1) Confidence 0.58 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2926634 Disease Relevance 0.07 Pain Relevance 0

General Comments

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