INT328554

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Context Info
Confidence 0.26
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.12
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (HDAC1) nucleoplasm (HDAC1) nucleolus (HDAC1)
nucleus (HDAC1) enzyme binding (HDAC1) transcription factor binding (HDAC1)
HDAC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
carbamazepine 4 67.68 Quite High
Bioavailability 1 50.00 Quite Low
Substantia nigra 1 17.12 Low Low
depression 9 5.00 Very Low Very Low Very Low
antiepileptic Drug 7 5.00 Very Low Very Low Very Low
gABA 6 5.00 Very Low Very Low Very Low
Lamotrigine 6 5.00 Very Low Very Low Very Low
addiction 6 5.00 Very Low Very Low Very Low
Migraine 4 5.00 Very Low Very Low Very Low
aspirin 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Spinal Muscular Atrophy 9 98.44 Very High Very High Very High
Disease 24 91.40 High High
Neurodegenerative Disease 1 79.24 Quite High
Neurological Disease 6 77.68 Quite High
Coma 2 76.52 Quite High
Heart Rate Under Development 1 76.00 Quite High
Apoptosis 15 66.88 Quite High
Toxicity 8 50.00 Quite Low
Cancer 26 15.16 Low Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, the specificity of target of several HDACi members decreases their effectiveness and could lead to the choice of less specific molecules, such as SAHA [28].
Regulation (target) of HDACi
1) Confidence 0.26 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2926634 Disease Relevance 1.12 Pain Relevance 0.03

General Comments

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