INT328627

Context Info Confidence 0.04 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.73 Pain Relevance 0

extracellular region (LGALS3, MUC16) plasma membrane (LGALS3, MUC16) cell differentiation (LGALS3) extracellular matrix organization (LGALS3) cytoplasm (LGALS3) extracellular space (MUC16)

LGALS3 (Homo sapiens) MUC16 (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammation 2 5.00 Inflammatory mediators 1 5.00 anesthesia 1 5.00 imagery 1 5.00

Disease Link Frequency Relevance Heat Syndrome 49 96.16 Dry Eye 23 92.40 Sjoegrens Syndrome 31 92.08 Cancer 1 69.96 Eye Disease 9 59.20 Disease 4 5.00 INFLAMMATION 3 5.00 Breast Cancer 2 5.00 Hypersensitivity 2 5.00 Disorders Of The Lacrimal System 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Recent work by Argueso et al. [49], however, suggests that, in vitro, it is the interaction of the carbohydrate binding protein galectin-3 with the carbohydrate portion of both MUC1 and MUC16 that creates a protective barrier to the penetration of dye such as rose bengal.

galectin-3 Binding (interaction) of MUC16

1) Confidence 0.04 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2927371 Disease Relevance 0.73 Pain Relevance 0

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