INT328742

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.40
Pain Relevance 1.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Mapk14) cell morphogenesis (Mapk14) response to stress (Mapk14)
cytoplasm (Mapk14) cytosol (Mapk14) nucleus (Mapk14)
Anatomy Link Frequency
nerve 1
Il1 (Mus musculus)
Mapk14 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 14 100.00 Very High Very High Very High
Lasting pain 1 98.52 Very High Very High Very High
Inflammatory mediators 2 95.20 Very High Very High Very High
Central nervous system 14 88.32 High High
Inflammation 103 87.12 High High
Spinal cord 21 86.72 High High
Arthritis 24 83.44 Quite High
Neuropathic pain 3 79.92 Quite High
Pain 6 71.16 Quite High
intrathecal 12 71.04 Quite High
Disease Link Frequency Relevance Heat
Stress 4 100.00 Very High Very High Very High
Nervous System Injury 1 99.96 Very High Very High Very High
Pain 6 98.52 Very High Very High Very High
INFLAMMATION 102 95.20 Very High Very High Very High
Necrosis 2 93.44 High High
Cancer 2 93.08 High High
Experimental Arthritis 7 84.16 Quite High
Neuropathic Pain 4 79.92 Quite High
Arthritis 24 58.48 Quite High
Arthropathy 1 34.04 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
After nerve injury, p38 is activated by several stimuli, including osmotic stress and cytokines such as IL-1 and TNF.
IL-1 Positive_regulation (activated) of p38 in nerve associated with stress, nervous system injury and cytokine
1) Confidence 0.01 Published 2010 Journal Curr Rheumatol Rep Section Body Doc Link PMC2927688 Disease Relevance 1.40 Pain Relevance 1.20

General Comments

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