INT328768

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Context Info
Confidence 0.19
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.61
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Gata6) DNA binding (Gata6) transcription factor binding (Gata6)
Gata6 (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 4 5.00 Very Low Very Low Very Low
Chronic pancreatitis 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Malignant Neoplastic Disease 3 93.52 High High
Pancreatic Cancer 28 77.88 Quite High
Adenocarcinoma 17 74.80 Quite High
Cancer 63 68.08 Quite High
Apoptosis 6 40.80 Quite Low
Chromosome Aberrations 3 30.92 Quite Low
Reprotox - General 1 1 10.04 Low Low
Metastasis 18 5.00 Very Low Very Low Very Low
Adhesions 7 5.00 Very Low Very Low Very Low
Aggression 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition to these target genes we identified an amplification of the chromosomal region 18q11.2 containing the gene for the transcription factor GATA-6, whose gain and overexpression may play an important and hitherto uninvestigated role in pancreatic carcinogenesis [30].
Positive_regulation (overexpression) of Gene_expression (overexpression) of GATA-6
1) Confidence 0.19 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2927995 Disease Relevance 0.61 Pain Relevance 0

General Comments

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