INT328778

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Context Info
Confidence 0.18
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.16
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (MMP10) extracellular space (MMP10) extracellular region (MMP10)
proteinaceous extracellular matrix (MMP10)
Anatomy Link Frequency
liver 1
MMP10 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 8 99.96 Very High Very High Very High
Chronic pancreatitis 2 51.04 Quite High
Inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatic Cancer 56 97.40 Very High Very High Very High
Cancer 126 92.88 High High
Adenocarcinoma 34 89.48 High High
Aggression 8 78.24 Quite High
Apoptosis 12 76.16 Quite High
Adhesions 14 75.52 Quite High
Pancreatitis 2 51.04 Quite High
Repression 2 41.60 Quite Low
Metastasis 36 34.24 Quite Low
Disease Progression 2 19.52 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recently, MMP-10 was shown to be specifically upregulated and involved in metastatic spread to the liver in xenografts of pancreatic cancer [41].
Positive_regulation (upregulated) of MMP-10 in liver associated with pancreatic cancer
1) Confidence 0.18 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2927995 Disease Relevance 1.11 Pain Relevance 0.24
Indeed, we found several MMPs (MMP-10, MMP-28) to be upregulated in PaCa 5061.
Positive_regulation (upregulated) of MMP-10 associated with metalloproteinase
2) Confidence 0.18 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2927995 Disease Relevance 1.05 Pain Relevance 0.19

General Comments

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