INT328820

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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Jak2) aging (Il6) histone binding (Jak2)
cytoplasm (Jak2) cytosol (Jak2) extracellular space (Il6)
Il6 (Rattus norvegicus)
Jak2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 29 95.04 Very High Very High Very High
Potency 26 93.12 High High
Inflammation 21 50.00 Quite Low
Arthritis 48 42.60 Quite Low
rheumatoid arthritis 22 41.48 Quite Low
psoriasis 3 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 20 50.00 Quite Low
Arthritis 52 42.60 Quite Low
Rheumatoid Arthritis 22 41.48 Quite Low
Disease 10 5.00 Very Low Very Low Very Low
Immunization 9 5.00 Very Low Very Low Very Low
Hematological Disease 4 5.00 Very Low Very Low Very Low
Psoriasis 3 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 3 5.00 Very Low Very Low Very Low
Reprotox - General 1 1 5.00 Very Low Very Low Very Low
Hepatocellular Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although the gp130 component of the IL-6 receptor complex can associate with JAK1, JAK2 or TYK2, JAK1 plays an essential role in cell signaling, since JAK1-deficient cells fail to respond to IL-6 or other gp130 cytokines [24].
IL-6 Binding (associate) of JAK2 associated with cytokine
1) Confidence 0.09 Published 2010 Journal J Inflamm (Lond) Section Body Doc Link PMC2928212 Disease Relevance 0 Pain Relevance 0.38

General Comments

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