INT328871

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.25
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (ZNF434) intracellular (ZNF434) DNA binding (ZNF434)
Anatomy Link Frequency
skin 1
ZNF434 (Homo sapiens)
Pain Link Frequency Relevance Heat
COX2 3 85.72 High High
Inflammation 33 78.32 Quite High
Inflammatory response 6 5.00 Very Low Very Low Very Low
cytokine 5 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Esophageal Disease 36 100.00 Very High Very High Very High
Necrosis 1 95.28 Very High Very High Very High
Cancer 25 94.92 High High
Breast Cancer 29 89.60 High High
INFLAMMATION 42 78.32 Quite High
Toxicity 20 54.64 Quite High
Pneumonia 36 52.00 Quite High
Nicotine Addiction 8 45.56 Quite Low
Non-small-cell Lung Cancer 8 5.00 Very Low Very Low Very Low
Lung Cancer 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The SNPs rs689465, rs689466, rs20417 and rs5275 were further studied: Their genotypic distributions followed Hardy-Weinberg equilibrium and the MAFs were not affected by gender or skin color.
Neg (not) Regulation (affected) of rs20417 in skin
1) Confidence 0.01 Published 2010 Journal BMC Cancer Section Abstract Doc Link PMC2992523 Disease Relevance 0.34 Pain Relevance 0
Three SNPs in PTGS2 modulated esophagitis risk in our patient population: rs20417, rs5275, and rs689470.
Regulation (modulated) of rs20417 associated with esophageal disease
2) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2928273 Disease Relevance 0.91 Pain Relevance 0.14

General Comments

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