INT328873

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.22
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (ZNF434) intracellular (ZNF434) DNA binding (ZNF434)
ZNF434 (Homo sapiens)
Pain Link Frequency Relevance Heat
COX2 3 83.56 Quite High
Inflammation 34 78.32 Quite High
cytokine 7 5.00 Very Low Very Low Very Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Esophageal Disease 36 99.34 Very High Very High Very High
Necrosis 1 93.12 High High
Cancer 43 92.76 High High
INFLAMMATION 46 78.32 Quite High
Breast Cancer 58 70.68 Quite High
Colon Cancer 2 54.16 Quite High
Toxicity 20 52.48 Quite High
Pneumonia 36 49.84 Quite Low
Nicotine Addiction 8 43.40 Quite Low
Non-small-cell Lung Cancer 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The SNPs rs689465, rs689466, rs20417 and rs5275, which showed a higher than 0.10 MAF in this first population subset, were selected for further characterization in a larger sample (Table 2).
Gene_expression (selected) of rs20417
1) Confidence 0.02 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2992523 Disease Relevance 0.13 Pain Relevance 0
The SNPs rs689465, rs689466, rs20417 and rs5275 were selected for the case-control study and appear to be the most frequent SNPs in other Western populations [16,21,23,25,51-58].
Gene_expression (selected) of rs20417
2) Confidence 0.02 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2992523 Disease Relevance 0.30 Pain Relevance 0
Three SNPs in PTGS2 modulated esophagitis risk in our patient population: rs20417, rs5275, and rs689470.
Gene_expression (rs20417) of rs20417 associated with esophageal disease
3) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2928273 Disease Relevance 0.79 Pain Relevance 0.14

General Comments

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