INT329066

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Context Info
Confidence 0.43
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.12
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (Tlr3) cytoplasm (Tlr3)
Anatomy Link Frequency
whiskers 4
Tlr3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 22 81.60 Quite High
Inflammatory mediators 2 78.76 Quite High
Central nervous system 2 20.68 Low Low
cytokine 12 6.88 Low Low
fifth nerve 6 5.00 Very Low Very Low Very Low
trigeminal ganglion 4 5.00 Very Low Very Low Very Low
isoflurane 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Inflammatory marker 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Viral Meningitis 64 99.80 Very High Very High Very High
INFLAMMATION 28 81.96 Quite High
Cold Sores 122 74.96 Quite High
Sprains And Strains 94 69.92 Quite High
Viral Infection 2 65.44 Quite High
Infection 58 63.84 Quite High
Herpes Simplex Virus 8 50.00 Quite Low
Disease 8 5.00 Very Low Very Low Very Low
Peripheral Arterial Disease 6 5.00 Very Low Very Low Very Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The levels of Tlr3 were increased at 12 hpi and 1 dpi in the whiskers area of the DA rats, while differences were significant also at later time points in PVG rats.
Positive_regulation (increased) of Gene_expression (levels) of Tlr3 in whiskers
1) Confidence 0.43 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2929186 Disease Relevance 0.33 Pain Relevance 0.04
However, in our HSE model an elevated expression of Tlr3 in the whiskers area was seen in the susceptible rat and we hypothesized that the susceptibility was not caused by low expression of Tlr3.
Positive_regulation (elevated) of Gene_expression (expression) of Tlr3 in whiskers associated with viral meningitis
2) Confidence 0.43 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2929186 Disease Relevance 0.80 Pain Relevance 0.04

General Comments

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