INT32908

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Context Info
Confidence 0.00
First Reported 1985
Last Reported 1985
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (ADCY1, Drd2) plasma membrane (ADCY1, Drd2) pigmentation (Drd2)
small molecule metabolic process (ADCY1) nucleus (ADCY1) GTPase activity (ADCY1)
Anatomy Link Frequency
neurons 1
ADCY1 (Homo sapiens)
Drd2 (Mus musculus)
Pain Link Frequency Relevance Heat
Dopamine 8 100.00 Very High Very High Very High
Enkephalin 1 94.52 High High
antagonist 3 89.00 High High
agonist 1 88.36 High High
Potency 2 86.84 High High
dopamine receptor 1 75.00 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These findings suggest that a D2 receptor mediates the inhibition of intracellular cyclic AMP formation by DA in striatal neurons in primary culture, and may do so by an interaction with the inhibitory guanine nucleotide regulatory protein of adenylate cyclase.
cyclase Binding (interaction) of D2 receptor in neurons associated with dopamine
1) Confidence 0.00 Published 1985 Journal Mol. Pharmacol. Section Abstract Doc Link 2987658 Disease Relevance 0 Pain Relevance 0.54

General Comments

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